Chondroitin sulfate is a naturally occurring substance in the cartilage of animals, such as cows, pigs and sharks.

Glucosamine is usually extracted from crustaceans, such as shrimp, crab or lobster, and is available in different forms. Glucosamine sulphate has been used in the Joint Support and no less than 500 mg.

Methylsulfonylmethane, often abbreviated as MSM, is an organic compound containing sulfur that occurs naturally in the human body. It is also found in various foods, such as fruits, vegetables, grains and animal products.